A hybrid correcting method considering heterozygous variations by a comprehensive probabilistic model

A hybrid correcting method considering heterozygous variations by a comprehensive probabilistic model

Abstract Background The emergence of the third generation sequencing technology, featuring longer read lengths, has demonstrated great advancement compared to the next generation sequencing technology and greatly promoted the biological research. However, the third generation sequencing data has a h...

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Bibliographic Details
Main Authors: Jiaqi Liu, Jiayin Wang, Xiao Xiao, Xin Lai, Daocheng Dai, Xuanping Zhang, Xiaoyan Zhu, Zhongmeng Zhao, Juan Wang, Zhimin Li
Format: Article
Language:English
Published: BMC 2020-11-01
Series:BMC Genomics
Subjects:
Sequencing analysis
PacBio sequencing
Sequencing error
Error correction method
Hybrid correction method
Heterozygous variant
Online Access:http://link.springer.com/article/10.1186/s12864-020-07008-9

Internet

http://link.springer.com/article/10.1186/s12864-020-07008-9

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