Aptamer loaded superparamagnetic beads for selective capturing and gentle release of activated protein C

Aptamer loaded superparamagnetic beads for selective capturing and gentle release of activated protein C

Abstract Activated protein C (APC) is a serine protease with anticoagulant and cytoprotective activities which make it an attractive target for diagnostic and therapeutic applications. In this work, we present one-step activation of APC from a commercial source of protein C (PC, Ceprotin) followed b...

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Bibliographic Details
Main Authors: Nasim Shahidi Hamedani, Felix Lucian Happich, Eva-Maria Klein, Heiko Rühl, Günter Mayer, Johannes Oldenburg, Jens Müller, Bernd Pötzsch
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-11198-5

Internet

https://doi.org/10.1038/s41598-022-11198-5

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