In silico Exploration of Interactions Between Potential COVID-19 Antiviral Treatments and the Pore of the hERG Potassium Channel—A Drug Antitarget

In silico Exploration of Interactions Between Potential COVID-19 Antiviral Treatments and the Pore of the hERG Potassium Channel—A Drug Antitarget

Background: In the absence of SARS-CoV-2 specific antiviral treatments, various repurposed pharmaceutical approaches are under investigation for the treatment of COVID-19. Antiviral drugs considered for this condition include atazanavir, remdesivir, lopinavir-ritonavir, and favipiravir. Whilst the c...

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Bibliographic Details
Main Authors: Ehab Al-Moubarak, Mohsen Sharifi, Jules C. Hancox
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
hERG
human ether-à-go-go–related gene
antiviral
atazanavir
lopinavir-ritonavir
remdesivir
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.645172/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2021.645172/full

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