Intention to Inform Relatives, Rates of Cascade Testing, and Preference for Patient-Mediated Communication in Families Concerned with Hereditary Breast and Ovarian Cancer and Lynch Syndrome: The Swiss CASCADE Cohort

Intention to Inform Relatives, Rates of Cascade Testing, and Preference for Patient-Mediated Communication in Families Concerned with Hereditary Breast and Ovarian Cancer and Lynch Syndrome: The Swiss CASCADE Cohort

Cascade screening for Tier 1 cancer genetic conditions is a significant public health intervention because it identifies untested relatives of individuals known to carry pathogenic variants associated with hereditary breast and ovarian cancer (HBOC) and Lynch syndrome (LS). The Swiss CASCADE is a fa...

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Bibliographic Details
Main Authors: Mahesh Sarki, Chang Ming, Souria Aissaoui, Nicole Bürki, Maria Caiata-Zufferey, Tobias Ephraim Erlanger, Rossella Graffeo-Galbiati, Karl Heinimann, Viola Heinzelmann-Schwarz, Christian Monnerat, Nicole Probst-Hensch, Manuela Rabaglio, Ursina Zürrer-Härdi, Pierre Olivier Chappuis, Maria C. Katapodi, on behalf of the CASCADE Consortium
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cancers
Subjects:
family-based cohort
family invitation
LASSO
public health genetics
Tier 1 genetic syndromes
untested relatives
Online Access:https://www.mdpi.com/2072-6694/14/7/1636

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https://www.mdpi.com/2072-6694/14/7/1636

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