Genetic variants in the G gamma-globin promoter modulate fetal hemoglobin expression in the Colombian population

Abstract Fetal hemoglobin (HbF) is a determining factor for the development of sickle cell anemia. High HbF levels lower the intensity of symptoms of this disease. HbF levels can vary in patients with sickle cell anemia and individuals without the disease. The purpose of this study was to identify t...

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Bibliographic Details
Main Authors: Cristian Fong, Yesica Mendoza, Guillermo Barreto
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2020-04-01
Series:Genetics and Molecular Biology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572020000400103&tlng=en