Titanium-Mediated Reduction of Carboxamides to Amines with Borane–Ammonia

In this study, the successful titanium tetrachloride-catalyzed reduction of aldehydes, ketones, carboxylic acids, and nitriles with borane–ammonia was extended to the reduction (deoxygenation) of a variety of aromatic and aliphatic pri-, sec- and tert-carboxamides, by changing the stoichiometry of t...

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Bibliographic Details
Main Authors: P. Veeraraghavan Ramachandran, Abdulkhaliq A. Alawaed, Aman Singh
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/12/4575