Comorbidity between Alzheimer’s disease and major depression: a behavioural and transcriptomic characterization study in mice

Comorbidity between Alzheimer’s disease and major depression: a behavioural and transcriptomic characterization study in mice

Abstract Background Major depression (MD) is the most prevalent psychiatric disease in the population and is considered a prodromal stage of the Alzheimer’s disease (AD). Despite both diseases having a robust genetic component, the common transcriptomic signature remains unknown. Methods We investig...

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Bibliographic Details
Main Authors: Ana Martín-Sánchez, Janet Piñero, Lara Nonell, Magdalena Arnal, Elena M. Ribe, Alejo Nevado-Holgado, Simon Lovestone, Ferran Sanz, Laura I. Furlong, Olga Valverde
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
Major depression
Gene Set Enrichment Analysis
Comorbidity
Transcriptome
Behaviour
Online Access:https://doi.org/10.1186/s13195-021-00810-x

Internet

https://doi.org/10.1186/s13195-021-00810-x

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