Tumor organoids: applications in cancer modeling and potentials in precision medicine

Abstract Cancer is a top-ranked life-threatening disease with intratumor heterogeneity. Tumor heterogeneity is associated with metastasis, relapse, and therapy resistance. These factors contribute to treatment failure and an unfavorable prognosis. Personalized tumor models faithfully capturing the t...

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Bibliographic Details
Main Authors: Hanxiao Xu, Dechao Jiao, Aiguo Liu, Kongming Wu
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Journal of Hematology & Oncology
Subjects:
Online Access:https://doi.org/10.1186/s13045-022-01278-4