Single‐cell characteristics and malignancy regulation of alpha‐fetoprotein‐producing gastric cancer

Abstract Objective To characterize alpha‐fetoprotein (AFP)‐producing gastric cancer (AFPGC) at the single‐cell level and to identify regulatory factors for AFP expression and malignancy. Methods ScRNA‐seq was performed on two tumors collected from patients with AFPGC. InferCNV and sub‐clustering wer...

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Bibliographic Details
Main Authors: Yanxia Mei, Ming Li, Jihang Wen, Xiangxing Kong, Jun Li
Format: Article
Language:English
Published: Wiley 2023-05-01
Series:Cancer Medicine
Subjects:
Online Access:https://doi.org/10.1002/cam4.5883