Clausena Harmandiana root extract attenuated cognitive impairments via reducing amyloid accumulation and neuroinflammation in Aβ1-42-induced rats

Clausena Harmandiana root extract attenuated cognitive impairments via reducing amyloid accumulation and neuroinflammation in Aβ1-42-induced rats

Abstract Background Alzheimer’s disease (AD) pathogenesis is associated with amyloid-β (Aβ)-induced neuroinflammation. In AD, the activation of microglia caused by Aβ accumulation is followed by the synthesis and release of pro-inflammatory cytokines, including interleukin-1β (IL-1β) and tumor necro...

Full description

Bibliographic Details
Main Authors: Nutchareeporn Nillert, Chantana Boonyarat, Jariya Umka Welbat, Komsun Bunreungthong, Ploenthip Puthongking, Wanassanun Pannangrong
Format: Article
Language:English
Published: BMC 2022-04-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Clausena harmandiana
Alzheimer’s disease
Amyloid-β
Neuroinflammation
Recognition memory
Online Access:https://doi.org/10.1186/s12906-022-03591-4

Internet

https://doi.org/10.1186/s12906-022-03591-4

Similar Items