Modelling seizure rates rather than time to an event within clinical trials of antiepileptic drugs

Abstract Background Predictive models within epilepsy are frequently developed via Cox’s proportional hazards models. These models estimate risk of a specified event such as 12-month remission. They are relatively simple to produce, have familiar output, and are useful to answer questions about shor...

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Bibliographic Details
Main Authors: Laura J. Bonnett, Jane L. Hutton, Anthony G. Marson
Format: Article
Language:English
Published: BMC 2020-04-01
Series:BMC Medical Research Methodology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12874-020-00965-5