Carbonic anhydrase inhibitory activity of phthalimide-capped benzene sulphonamide derivatives

Carbonic anhydrase inhibitory activity of phthalimide-capped benzene sulphonamide derivatives

AbstractA series of phthalimide-capped benzene sulphonamides (1–22) reported by our group for dengue protease inhibitory activity have been evaluated for their carbonic anhydrase (hCA, EC 4.2.1.1) inhibitory activity against hCA I, hCA II. Compounds 1, 3, 10, and 15 showed hCA I inhibition, whereas...

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Bibliographic Details
Main Authors: Deepak Shilkar, Mohd Usman Mohd Siddique, Silvia Bua, Sabina Yasmin, Mrunali Patil, Ajay Kumar Timiri, Claudiu T. Supuran, Venkatesan Jayaprakash
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
Carbonic anhydrase
phthalyl sulphamoyl derivatives
molecular docking
molecular dynamics
Online Access:https://www.tandfonline.com/doi/10.1080/14756366.2023.2235089

Internet

https://www.tandfonline.com/doi/10.1080/14756366.2023.2235089

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