Analytical Performance of a Highly Sensitive System to Detect Gene Variants Using Next-Generation Sequencing for Lung Cancer Companion Diagnostics

Analytical Performance of a Highly Sensitive System to Detect Gene Variants Using Next-Generation Sequencing for Lung Cancer Companion Diagnostics

The recent increase in the number of molecular targeted agents for lung cancer has led to the demand for the simultaneous testing of multiple genes. Although gene panels using next-generation sequencing (NGS) are ideal, conventional panels require a high tumor content, and biopsy samples often do no...

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Bibliographic Details
Main Authors: Kikuya Kato, Jiro Okami, Harumi Nakamura, Keiichiro Honma, Yoshiharu Sato, Seiji Nakamura, Yoji Kukita, Shin-ichi Nakatsuka, Masahiko Higashiyama
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Diagnostics
Subjects:
non-small cell lung carcinoma
molecular targeted therapy
companion diagnostics
next-generation sequencing
gene panel
Online Access:https://www.mdpi.com/2075-4418/13/8/1476

Internet

https://www.mdpi.com/2075-4418/13/8/1476

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