West Nile virus infectious replicon particles generated using a packaging-restricted cell line is a safe reporter system

Abstract West Nile virus (WNV) is a neurotropic pathogen which causes zoonotic disease in humans. Recently, there have been an increasing number of infected cases and there are no clinically approved vaccines or effective drugs to treat WNV infections in humans. The purpose of this study was to faci...

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Bibliographic Details
Main Authors: Wei Li, Le Ma, Li-Ping Guo, Xiao-Lei Wang, Jing-Wei Zhang, Zhi-Gao Bu, Rong-Hong Hua
Format: Article
Language:English
Published: Nature Portfolio 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-03670-4