Donor- and isolation-related predictive factors of in vitro secretory function of cultured human islets

Donor- and isolation-related predictive factors of in vitro secretory function of cultured human islets

Background and aimsHuman islet preparations designated for research exhibit diverse insulin-secretory profiles. This study aims to assess the impact of donor- and isolation-related factors on in vitro islet secretory function.MethodsA retrospective analysis of 46 isolations from 23 pancreata discard...

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Bibliographic Details
Main Authors: Antoine Buemi, Nizar I. Mourad, Jérôme Ambroise, Delphine Hoton, Arnaud Devresse, Tom Darius, Nada Kanaan, Pierre Gianello, Michel Mourad
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Endocrinology
Subjects:
islet isolation
islet perifusion
islet function
donor predictive variables
pancreas histology
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2024.1345351/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2024.1345351/full

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