Mechanically tuned 3 dimensional hydrogels support human mammary fibroblast growth and viability

Abstract Background Carcinoma associated fibroblasts (CAFs or myofibroblasts) are activated fibroblasts which participate in breast tumor growth, angiogenesis, invasion, metastasis and therapy resistance. As such, recent efforts have been directed toward understanding the factors responsible for act...

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Bibliographic Details
Main Authors: Kathryn Woods, Catlyn Thigpen, Jennifer Peyling Wang, Hana Park, Abigail Hielscher
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Cell Biology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12860-017-0151-y