Characterization of Cetacean Proline-Rich Antimicrobial Peptides Displaying Activity against ESKAPE Pathogens

Characterization of Cetacean Proline-Rich Antimicrobial Peptides Displaying Activity against ESKAPE Pathogens

Proline-rich antimicrobial peptides (PrAMPs) may be a valuable weapon against multi-drug resistant pathogens, combining potent antimicrobial activity with low cytotoxicity. We have identified novel PrAMPs from five cetacean species (cePrAMPs), and characterized their potency, mechanism of action and...

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Bibliographic Details
Main Authors: Riccardo Sola, Mario Mardirossian, Bertrand Beckert, Laura Sanghez De Luna, Dennis Prickett, Alessandro Tossi, Daniel N. Wilson, Marco Scocchi
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Cetacea</i>
antimicrobial peptide
proline-rich
cathelicidin
protein synthesis
membrane permeabilization
Online Access:https://www.mdpi.com/1422-0067/21/19/7367

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https://www.mdpi.com/1422-0067/21/19/7367

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