Murine SEC24D can substitute functionally for SEC24C during embryonic development
Abstract The COPII component SEC24 mediates the recruitment of transmembrane cargos or cargo adaptors into newly forming COPII vesicles on the ER membrane. Mammalian genomes encode four Sec24 paralogs (Sec24a-d), with two subfamilies based on sequence homology (SEC24A/B and C/D), though little is kn...
Main Authors: | , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-10-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-00579-x |