Murine SEC24D can substitute functionally for SEC24C during embryonic development

Abstract The COPII component SEC24 mediates the recruitment of transmembrane cargos or cargo adaptors into newly forming COPII vesicles on the ER membrane. Mammalian genomes encode four Sec24 paralogs (Sec24a-d), with two subfamilies based on sequence homology (SEC24A/B and C/D), though little is kn...

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Bibliographic Details
Main Authors: Elizabeth J. Adams, Rami Khoriaty, Anna Kiseleva, Audrey C. A. Cleuren, Kärt Tomberg, Martijn A. van der Ent, Peter Gergics, Vi T. Tang, Guojing Zhu, Mark J. Hoenerhoff, K. Sue O’Shea, Thomas L. Saunders, David Ginsburg
Format: Article
Language:English
Published: Nature Portfolio 2021-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-00579-x