Formation of the mutagenic DNA lesion 1,N2-ethenoguanine induced by heated cooking oil and identification of causative agents

Abstract Background The DNA-damaging compounds in heated cooking oil were identified as guanosine adducts. Heated vegetable oil was subjected to deep-frying conditions at 170 °C for 45 min, reacted with isopropylidene guanosine (ipG) at pH 7.4, and the resulting compounds were separated by high-perf...

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Bibliographic Details
Main Authors: Hiroshi Kasai, Kazuaki Kawai
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Genes and Environment
Subjects:
Online Access:https://doi.org/10.1186/s41021-023-00284-3