Concurrent KRAS p.G12C mutation and ANK3::RET fusion in a patient with metastatic colorectal cancer: a case report

Concurrent KRAS p.G12C mutation and ANK3::RET fusion in a patient with metastatic colorectal cancer: a case report

Abstract Background Colorectal cancer (CRC) frequently involves mutations in the KRAS gene, impacting therapeutic strategies and prognosis. The occurrence of KRAS mutations typically precludes the presence of RET fusions, with current medical literature suggesting a mutual exclusivity between these...

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Bibliographic Details
Main Authors: Tillmann Bedau, Carina Heydt, Udo Siebolts, Thomas Zander, Max Kraemer, Heike Loeser, Reinhard Buettner, Alexander Quaas
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Diagnostic Pathology
Subjects:
KRAS p.G12C mutation
ANK3::RET fusion.
Metastatic colorectal cancer
Molecular diagnostics
Targeted therapy
Precision oncology
Online Access:https://doi.org/10.1186/s13000-024-01478-1

Internet

https://doi.org/10.1186/s13000-024-01478-1

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