Infection of ferrets with wild type-based recombinant canine distemper virus overwhelms the immune system and causes fatal systemic disease

Infection of ferrets with wild type-based recombinant canine distemper virus overwhelms the immune system and causes fatal systemic disease

ABSTRACT Canine distemper virus (CDV) causes systemic infection resulting in severe and often fatal disease in a large spectrum of animal host species. The virus is closely related to measles virus and targets myeloid, lymphoid, and epithelial cells, but CDV is more virulent and the infection spread...

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Bibliographic Details
Main Authors: Brigitta M. Laksono, Dagmar Roelofs, Anouskha D. Comvalius, Katharina S. Schmitz, Laurine C. Rijsbergen, Daryl Geers, Sham Nambulli, Peter van Run, W. Paul Duprex, Judith M. A. van den Brand, Rory D. de Vries, Rik L. de Swart
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:mSphere
Subjects:
morbillivirus
canine distemper virus
immunopathogenesis
ferrets
Online Access:https://journals.asm.org/doi/10.1128/msphere.00082-23

Internet

https://journals.asm.org/doi/10.1128/msphere.00082-23

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