Chronic nicotine impairs the angiogenic capacity of human induced pluripotent stem cell-derived endothelial cells in a murine model of peripheral arterial disease

Chronic nicotine impairs the angiogenic capacity of human induced pluripotent stem cell-derived endothelial cells in a murine model of peripheral arterial disease

Objective: Lifestyle choices such as tobacco and e-cigarette use are a risk factor for peripheral arterial disease (PAD) and may influence therapeutic outcomes. The effect of chronic nicotine exposure on the angiogenic capacity of human induced pluripotent stem cell-derived endothelial cells (iPSC-E...

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Bibliographic Details
Main Authors: Alex H.P. Chan, PhD, Caroline Hu, BS, Gladys C.F. Chiang, BS, Chisomaga Ekweume, BS, Ngan F. Huang, PhD
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:JVS - Vascular Science
Subjects:
Endothelial cell
Angiogenesis
Limb ischemia
Nicotine
Induced pluripotent stem cell
Peripheral arterial disease
Online Access:http://www.sciencedirect.com/science/article/pii/S2666350323000196

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http://www.sciencedirect.com/science/article/pii/S2666350323000196

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