The in vitro gastrointestinal digestion-associated protein corona of polystyrene nano- and microplastics increases their uptake by human THP-1-derived macrophages

The in vitro gastrointestinal digestion-associated protein corona of polystyrene nano- and microplastics increases their uptake by human THP-1-derived macrophages

Abstract Background Micro- and nanoplastics (MNPs) represent one of the most widespread environmental pollutants of the twenty-first century to which all humans are orally exposed. Upon ingestion, MNPs pass harsh biochemical conditions within the gastrointestinal tract, causing a unique protein coro...

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Bibliographic Details
Main Authors: Hugo Brouwer, Mojtaba Porbahaie, Sjef Boeren, Mathias Busch, Hans Bouwmeester
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Particle and Fibre Toxicology
Subjects:
Macrophage
In vitro gastrointestinal digestion
Polystyrene
THP-1
Endocytosis
Protein corona
Online Access:https://doi.org/10.1186/s12989-024-00563-z

Internet

https://doi.org/10.1186/s12989-024-00563-z

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