Distinct Contributions of Different Domains within the HIV-1 Gag Polyprotein to Specific and Nonspecific Interactions with RNA

Viral genomic RNA is packaged into virions with high specificity and selectivity. However, in vitro the Gag specificity towards viral RNA is obscured when measured in buffers containing physiological salt. Interestingly, when the binding is challenged by increased salt concentration, the addition of...

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Hlavní autoři: Tomas Kroupa, Siddhartha A. K. Datta, Alan Rein
Médium: Článek
Jazyk:English
Vydáno: MDPI AG 2020-04-01
Edice:Viruses
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On-line přístup:https://www.mdpi.com/1999-4915/12/4/394