Ion mobility-tandem mass spectrometry of mucin-type O-glycans

Ion mobility-tandem mass spectrometry of mucin-type O-glycans

Abstract The dense O-glycosylation of mucins plays an important role in the defensive properties of the mucus hydrogel. Aberrant glycosylation is often correlated with inflammation and pathology such as COPD, cancer, and Crohn’s disease. The inherent complexity of glycans and the diversity in the O-...

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Bibliographic Details
Main Authors: Leïla Bechtella, Jin Chunsheng, Kerstin Fentker, Güney R. Ertürk, Marc Safferthal, Łukasz Polewski, Michael Götze, Simon Y. Graeber, Gaël M. Vos, Weston B. Struwe, Marcus A. Mall, Philipp Mertins, Niclas G. Karlsson, Kevin Pagel
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-46825-4

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https://doi.org/10.1038/s41467-024-46825-4

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