The Role of Intracellular Ca<sup>2+</sup> and Mitochondrial ROS in Small Aβ<sub>1-42</sub> Oligomer-Induced Microglial Death

Alzheimer’s disease (AD) is the most common form of dementia worldwide, and it contributes up to 70% of cases. AD pathology involves abnormal amyloid beta (Aβ) accumulation, and the link between the Aβ<sub>1-42</sub> structure and toxicity is of major interest. NMDA receptors (NMDAR) are...

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Bibliographic Details
Main Authors: Aiste Jekabsone, Silvija Jankeviciute, Katryna Pampuscenko, Vilmante Borutaite, Ramune Morkuniene
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/15/12315