The Role of Intracellular Ca<sup>2+</sup> and Mitochondrial ROS in Small Aβ<sub>1-42</sub> Oligomer-Induced Microglial Death
Alzheimer’s disease (AD) is the most common form of dementia worldwide, and it contributes up to 70% of cases. AD pathology involves abnormal amyloid beta (Aβ) accumulation, and the link between the Aβ<sub>1-42</sub> structure and toxicity is of major interest. NMDA receptors (NMDAR) are...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-08-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/24/15/12315 |