Targeting the Pentose Phosphate Pathway for SARS-CoV-2 Therapy

Targeting the Pentose Phosphate Pathway for SARS-CoV-2 Therapy

SARS-CoV-2 is causing the coronavirus disease 2019 (COVID-19) pandemic, for which effective pharmacological therapies are needed. SARS-CoV-2 induces a shift of the host cell metabolism towards glycolysis, and the glycolysis inhibitor 2-deoxy-<span style="font-variant: small-caps;">d&...

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Bibliographic Details
Main Authors: Denisa Bojkova, Rui Costa, Philipp Reus, Marco Bechtel, Mark-Christian Jaboreck, Ruth Olmer, Ulrich Martin, Sandra Ciesek, Martin Michaelis, Jindrich Cinatl
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Metabolites
Subjects:
SARS-CoV-2
COVID-19
antiviral therapy
pentose phosphate pathway
oxythiamine
benfooxythiamine
Online Access:https://www.mdpi.com/2218-1989/11/10/699

Internet

https://www.mdpi.com/2218-1989/11/10/699

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