Inhibition of immunothrombosis does not affect pathogen capture and does not promote bacterial dissemination in a mouse model of sepsis

After infection, neutrophils release neutrophil extracellular traps (NETs), decondensed DNA fibers decorated with both nuclear proteins and proteins derived from intracellular granules. These structures have a fundamental role in the development of immunothrombosis; a physiological process mediated...

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Bibliographic Details
Main Authors: Agostina Carestia, Rachelle P. Davis, Lauren Davis, Craig N. Jenne
Format: Article
Language:English
Published: Taylor & Francis Group 2020-10-01
Series:Platelets
Subjects:
Online Access:http://dx.doi.org/10.1080/09537104.2019.1704711