Inhibition of immunothrombosis does not affect pathogen capture and does not promote bacterial dissemination in a mouse model of sepsis
After infection, neutrophils release neutrophil extracellular traps (NETs), decondensed DNA fibers decorated with both nuclear proteins and proteins derived from intracellular granules. These structures have a fundamental role in the development of immunothrombosis; a physiological process mediated...
Main Authors: | Agostina Carestia, Rachelle P. Davis, Lauren Davis, Craig N. Jenne |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2020-10-01
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Series: | Platelets |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/09537104.2019.1704711 |
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