Novel insights in antimicrobial and immunomodulatory mechanisms of action of PepBiotics CR-163 and CR-172

Novel insights in antimicrobial and immunomodulatory mechanisms of action of PepBiotics CR-163 and CR-172

ABSTRACT: Objectives: Our group recently developed a new group of antimicrobial peptides termed PepBiotics, of which peptides CR-163 and CR-172 showed optimized antibacterial activity against Pseudomonas aeruginosa and Staphylococcus aureus without inducing antimicrobial resistance. In this study,...

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Bibliographic Details
Main Authors: Nico van Os, Ali Javed, Femke Broere, Albert van Dijk, Melanie D. Balhuizen, Martin van Eijk, Suzan H.M. Rooijakkers, Bart W. Bardoel, Dani A.C. Heesterbeek, Henk P. Haagsman, Edwin Veldhuizen
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
Antimicrobial peptide
Membrane
Peptide therapeutic
Antimicrobial resistance
Immunomodulation
LPS neutralization
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716522001758

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http://www.sciencedirect.com/science/article/pii/S2213716522001758

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