Trophoblast derived extracellular vesicles specifically alter the transcriptome of endometrial cells and may constitute a critical component of embryo-maternal communication

Trophoblast derived extracellular vesicles specifically alter the transcriptome of endometrial cells and may constitute a critical component of embryo-maternal communication

Abstract Background The period of time when the embryo and the endometrium undergo significant morphological alterations to facilitate a successful implantation—known as “window of implantation”—is a critical moment in human reproduction. Embryo and the endometrium communicate extensively during thi...

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Bibliographic Details
Main Authors: Kasun Godakumara, James Ord, Freddy Lättekivi, Keerthie Dissanayake, Janeli Viil, Nageswara Rao Boggavarapu, Omid R Faridani, Kersti Jääger, Agne Velthut-Meikas, Ülle Jaakma, Andres Salumets, Alireza Fazeli
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Reproductive Biology and Endocrinology
Subjects:
Embryo-maternal communication
Extracellular vesicles
miRNA signalling
RNA-sequencing
Online Access:https://doi.org/10.1186/s12958-021-00801-5

Internet

https://doi.org/10.1186/s12958-021-00801-5

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