Shift of N-MYC Oncogene Expression in AML Patients Carrying the FLT3-ITD Mutation

Shift of N-MYC Oncogene Expression in AML Patients Carrying the FLT3-ITD Mutation

Mutations in the <i>FLT3</i> gene not only lead to abnormalities in its structure and function, but also affect the expression of other genes involved in leukemogenesis. This study evaluated the expression of genes that are more characteristic of neuroblastoma but less studied in leukemi...

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Bibliographic Details
Main Authors: Konstantin Bogdanov, Ekaterina Kudryavtseva, Yulia Fomicheva, Irina Churkina, Elza Lomaia, Larisa Girshova, Yuri Osipov, Andrey Zaritskey
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Pathophysiology
Subjects:
acute myeloid leukemia
<i>FLT3-ITD</i> allelic load
<i>N-MYC</i> oncogene expression
Online Access:https://www.mdpi.com/1873-149X/30/3/24

Internet

https://www.mdpi.com/1873-149X/30/3/24

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