Morphologically intact airways in lung fibrosis have an abnormal proteome

Abstract Honeycombing is a histological pattern consistent with Usual Interstitial Pneumonia (UIP). Honeycombing refers to cystic airways located at sites of dense fibrosis with marked mucus accumulation. Utilizing laser capture microdissection coupled mass spectrometry (LCM-MS), we interrogated the...

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Bibliographic Details
Main Authors: Jeremy A. Herrera, Lewis A. Dingle, M. Angeles Monetero, Rajamiyer V. Venkateswaran, John F. Blaikley, Felice Granato, Stella Pearson, Craig Lawless, David J. Thornton
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Respiratory Research
Online Access:https://doi.org/10.1186/s12931-023-02400-x