Thymic Exhaustion and Increased Immune Activation Are the Main Mechanisms Involved in Impaired Immunological Recovery of HIV-Positive Patients under ART

Thymic Exhaustion and Increased Immune Activation Are the Main Mechanisms Involved in Impaired Immunological Recovery of HIV-Positive Patients under ART

Decades of studies in antiretroviral therapy (ART) have passed, and the mechanisms that determine impaired immunological recovery in HIV-positive patients receiving ART have not been completely elucidated yet. Thus, T-lymphocytes immunophenotyping and cytokines levels were analyzed in 44 ART-treated...

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Bibliographic Details
Main Authors: Maria Carolina Dos Santos Guedes, Wlisses Henrique Veloso Carvalho-Silva, José Leandro Andrade-Santos, Maria Carolina Accioly Brelaz-de-Castro, Fabrício Oliveira Souto, Rafael Lima Guimarães
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Viruses
Subjects:
AIDS
immunological non-responders
antiretroviral therapy
CD4+ T cell reconstitution
immune activation
Online Access:https://www.mdpi.com/1999-4915/15/2/440

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https://www.mdpi.com/1999-4915/15/2/440

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