CCR6+ group 3 innate lymphoid cells accumulate in inflamed joints in rheumatoid arthritis and produce Th17 cytokines

CCR6+ group 3 innate lymphoid cells accumulate in inflamed joints in rheumatoid arthritis and produce Th17 cytokines

Abstract Background Recent studies show that innate lymphoid cells (ILCs) contribute to the development of chronic inflammation and autoimmune disease. In this study, we assessed the ILC function in the development of rheumatoid arthritis (RA). Methods In a mouse model of collagen-induced arthritis...

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Bibliographic Details
Main Authors: Ayako Takaki-Kuwahara, Yojiro Arinobu, Kohta Miyawaki, Hisakata Yamada, Hirofumi Tsuzuki, Kensuke Irino, Masahiro Ayano, Yasutaka Kimoto, Hiroki Mitoma, Mitsuteru Akahoshi, Hiroshi Tsukamoto, Takahiko Horiuchi, Hiroaki Niiro, Koichi Akashi
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Arthritis Research & Therapy
Subjects:
Innate lymphoid cells
Rheumatoid arthritis
CCR6
Th17 cytokines
Online Access:http://link.springer.com/article/10.1186/s13075-019-1984-x

Internet

http://link.springer.com/article/10.1186/s13075-019-1984-x

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