SPTBN1 Prevents Primary Osteoporosis by Modulating Osteoblasts Proliferation and Differentiation and Blood Vessels Formation in Bone

SPTBN1 Prevents Primary Osteoporosis by Modulating Osteoblasts Proliferation and Differentiation and Blood Vessels Formation in Bone

Osteoporosis is a common systemic skeletal disorder that leads to increased bone fragility and increased risk of fracture. Although βII-Spectrin (SPTBN1) has been reported to be involved in the development of various human cancers, the function and underlying molecular mechanisms of SPTBN1 in primar...

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Bibliographic Details
Main Authors: Xuejuan Xu, Jiayi Yang, Yanshi Ye, Guoqiang Chen, Yinhua Zhang, Hangtian Wu, Yuqian Song, Meichen Feng, Xiaoting Feng, Xingying Chen, Xiao Wang, Xu Lin, Xiaochun Bai, Jie Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
osteoporosis
osteoblast
SPTBN1
VEGF
STAT1/Smad3 pathway 3
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.653724/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.653724/full

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