The role of p53 in the DNA damage-related ubiquitylation of S2P RNAPII.

DNA double-strand breaks are one of the most deleterious lesions for the cells, therefore understanding the macromolecular interactions of the DNA repair-related mechanisms is essential. DNA damage triggers transcription silencing at the damage site, leading to the removal of the elongating RNA poly...

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Bibliographic Details
Main Authors: Barbara N Borsos, Vasiliki Pantazi, Zoltán G Páhi, Hajnalka Majoros, Zsuzsanna Ujfaludi, Ivett Berzsenyi, Tibor Pankotai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0267615