Detection of 11q23 (MLL) rearrangements in infant acute lymphoblastic leukemia

Detection of 11q23 (MLL) rearrangements in infant acute lymphoblastic leukemia

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117 cases of infant acute lymphoblastic leukemia without Down syndrome (aged from 1 to 365 days) were included in the current study.Rearrangements of 11q23 (MLL) were revealed in 74 (63.2 %) patients. Among this group the most common rearrangement was t(4;11) q21;q23)/MLL-AF4 detected in 63.5 % case...

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Bibliographic Details
Main Authors: G. A. Tsaur, A. M. Popov, O. V. Aleynikova, E. G. Boychenko, T. Yu. Verzhbitskaya, E. V. Volochnik, A. S. Ivanova, O. V. Kalennik, S. Yu. Kovalev, K. L. Kondtratchik, A. M. Kustanovich, E. S. Lapotentova, D. V. Litvinov, I. S. Martynkevich, N. V. Myakova, T. V. Nasedkina, V. A. Ovsepyan, Yu. V. Olshanskaya, O. M. Plehanova, A. V. Popa, T. O. Riger, L. I. Savelyev, O. V. Streneva, M. V. Strigaleva, I. V. Shmunk, E. V. Shorikov, L. G. Fechina
Format: Article
Language:Russian
Published: ABV-press 2014-07-01
Series:Онкогематология
Subjects:
acute lymphoblastic leukemia
infants
translocation 11q23
mll rearrangements
Online Access:https://oncohematology.abvpress.ru/ongm/article/view/91

Internet

https://oncohematology.abvpress.ru/ongm/article/view/91

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