Production of CFTR Mutant Gene Model by Homologous Recombination System
Objective: The most common mutation in cystic fibrosis (CF), (ΔF508-CFTR), results in impaired protein maturation,folding and transportation to the surface of the cell. As a consequence of impaired protein maturation and/or transport from the extracellular matrix to the cell, different systems are i...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Royan Institute (ACECR), Tehran
2022-10-01
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| Series: | Cell Journal |
| Subjects: | |
| Online Access: | https://www.celljournal.org/article_253364_7998671eee9511a8abcb876a88e8d55e.pdf |