Hypoxia Primes Human ISCs for Interleukin-Dependent Rescue of Stem Cell ActivitySummary

Hypoxia Primes Human ISCs for Interleukin-Dependent Rescue of Stem Cell ActivitySummary

Background and Aims: Hypoxia in the intestinal epithelium can be caused by acute ischemic events or chronic inflammation in which immune cell infiltration produces inflammatory hypoxia starving the mucosa of oxygen. The epithelium has the capacity to regenerate after some ischemic and inflammatory c...

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Bibliographic Details
Main Authors: Kristina R. Rivera, R. Jarrett Bliton, Joseph Burclaff, Michael J. Czerwinski, Jintong Liu, Jessica M. Trueblood, Caroline M. Hinesley, Keith A. Breau, Halston E. Deal, Shlok Joshi, Vladimir A. Pozdin, Ming Yao, Amanda L. Ziegler, Anthony T. Blikslager, Michael A. Daniele, Scott T. Magness
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Inflammatory Hypoxia
Microphysiological System
Intestinal Stem Cells
Stem Cell Priming
Oxygen Sensor
Cytokines
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X23001443

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http://www.sciencedirect.com/science/article/pii/S2352345X23001443

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