Des-acyl ghrelin reduces alcohol intake and alcohol-induced reward in rodents

Des-acyl ghrelin reduces alcohol intake and alcohol-induced reward in rodents

Abstract The mechanisms contributing to alcohol use disorder (AUD) are complex and the orexigenic peptide ghrelin, which enhances alcohol reward, is implied as a crucial modulator. The major proportion of circulating ghrelin is however the non-octanoylated form of ghrelin, des-acyl ghrelin (DAG), wh...

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Bibliographic Details
Main Authors: Sarah Witley, Christian E. Edvardsson, Cajsa Aranäs, Maximilian Tufvesson-Alm, Darta Stalberga, Henrik Green, Jesper Vestlund, Elisabet Jerlhag
Format: Article
Language:English
Published: Nature Publishing Group 2024-07-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-024-02996-8

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https://doi.org/10.1038/s41398-024-02996-8

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