Does Genotype-Specific Phenotype in Patients with Multiple Endocrine Neoplasia Type 2 Occur as Current Guidelines Predict?

Does Genotype-Specific Phenotype in Patients with Multiple Endocrine Neoplasia Type 2 Occur as Current Guidelines Predict?

The clinical manifestation of multiple endocrine neoplasia type 2 (MEN2) in terms of developing medullary thyroid cancer (MTC), pheochromocytoma (PCC), and/or primary hyperparathyroidism (PHPT) is related to the respective pathogenic variant of the <i>RET</i> proto-oncogene. The aim of t...

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Bibliographic Details
Main Authors: Teresa Binter, Sabina Baumgartner-Parzer, Marie Helene Schernthaner-Reiter, Melisa Arikan, Lindsay Hargitai, Martin Bruno Niederle, Bruno Niederle, Christian Scheuba, Philipp Riss
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Cancers
Subjects:
multiple endocrine neoplasia type 2
hereditary medullary thyroid carcinoma
c-cell hyperplasia
pheochromocytoma
primary hyperparathyroidism
<i>RET</i> mutation
Online Access:https://www.mdpi.com/2072-6694/16/3/494

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https://www.mdpi.com/2072-6694/16/3/494

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