Prolyl dihydroxylation of unassembled uS12/Rps23 regulates fungal hypoxic adaptation

Prolyl dihydroxylation of unassembled uS12/Rps23 regulates fungal hypoxic adaptation

The prolyl-3,4-dihydroxylase Ofd1 and nuclear import adaptor Nro1 regulate the hypoxic response in fission yeast by controlling activity of the sterol regulatory element-binding protein transcription factor Sre1. Here, we identify an extra-ribosomal function for uS12/Rps23 central to this regulatory...

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Bibliographic Details
Main Authors: Sara J Clasen, Wei Shao, He Gu, Peter J Espenshade
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-10-01
Series:eLife
Subjects:
SREBP
ribosome
uS12
nuclear import
prolyl hydroxylation
extra-ribosomal
Online Access:https://elifesciences.org/articles/28563

Internet

https://elifesciences.org/articles/28563

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