Modified UCN2 peptide treatment improves skeletal muscle mass and function in mouse models of obesity‐induced insulin resistance

Modified UCN2 peptide treatment improves skeletal muscle mass and function in mouse models of obesity‐induced insulin resistance

Abstract Background Type 2 diabetes and obesity are often seen concurrently with skeletal muscle wasting, leading to further derangements in function and metabolism. Muscle wasting remains an unmet need for metabolic disease, and new approaches are warranted. The neuropeptide urocortin 2 (UCN2) and...

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Bibliographic Details
Main Authors: Melissa L. Borg, Julie Massart, Thais De Castro Barbosa, Adrià Archilla‐Ortega, Jonathon A.B. Smith, Johanna T. Lanner, Jorge Alsina‐Fernandez, Benjamin Yaden, Alexander E. Culver, Håkan K.R. Karlsson, Joseph T. Brozinick, Juleen R. Zierath
Format: Article
Language:English
Published: Wiley 2021-10-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Muscle wasting
Obesity
Diabetes
Insulin resistance
Exercise
Therapy
Online Access:https://doi.org/10.1002/jcsm.12746

Internet

https://doi.org/10.1002/jcsm.12746

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