SPARC: Structural properties associated with residue constraints

SPARC: Structural properties associated with residue constraints

SPARC facilitates the generation of plausible hypotheses regarding underlying biochemical mechanisms by structurally characterizing protein sequence constraints. Such constraints appear as residues co-conserved in functionally related subgroups, as subtle pairwise correlations (i.e., direct coupling...

Full description

Bibliographic Details
Main Authors: Andrew F. Neuwald, Hui Yang, B. Tracy Nixon
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Bayesian
Markov chain Monte Carlo
Direct coupling analysis
Computer algorithms
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037022001222

Internet

http://www.sciencedirect.com/science/article/pii/S2001037022001222

Similar Items