Transcriptional Factor Repertoire of Breast Cancer in 3D Cell Culture Models

Transcriptional Factor Repertoire of Breast Cancer in 3D Cell Culture Models

Intratumor heterogeneity of breast cancer is driven by extrinsic factors from the tumor microenvironment (TME) as well as tumor cell–intrinsic parameters including genetic, epigenetic, and transcriptomic traits. The extracellular matrix (ECM), a major structural component of the TME, impacts every s...

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Bibliographic Details
Main Authors: Hande Özkan, Deniz Gülfem Öztürk, Gozde Korkmaz
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cancers
Subjects:
breast cancer
tumor heterogeneity
three-dimensional (3D) culture
transcription factor
extracellular matrix
Online Access:https://www.mdpi.com/2072-6694/14/4/1023

Internet

https://www.mdpi.com/2072-6694/14/4/1023

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