Developing a Method to Estimate the Downstream Metabolite Signals from Hyperpolarized [1-<sup>13</sup>C]Pyruvate

Hyperpolarized carbon-13 MRI has the advantage of allowing the study of glycolytic flow in vivo or in vitro dynamically in real-time. The apparent exchange rate constant of a metabolite dynamic signal reflects the metabolite changes of a disease. Downstream metabolites can have a low signal-to-noise...

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Bibliographic Details
Main Authors: Ching-Yi Hsieh, Cheng-Hsuan Sung, Yi-Liang (Eric) Shen, Ying-Chieh Lai, Kuan-Ying Lu, Gigin Lin
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/22/15/5480