The neutrophil elastase inhibitor, sivelestat, attenuates acute lung injury in patients with cardiopulmonary bypass

The neutrophil elastase inhibitor, sivelestat, attenuates acute lung injury in patients with cardiopulmonary bypass

BackgroundThe sivelestat is a neutrophil elastase inhibitor thought to have an effect against acute lung injury (ALI) in patients after scheduled cardiac surgery. However, the beneficial effect of sivelestat in patients undergoing emergent cardiovascular surgery remains unclear. We aim to evaluate t...

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Bibliographic Details
Main Authors: Tuo Pan, Tayierjiang Tuoerxun, Xi Chen, Cheng-Jin Yang, Chen-Yu Jiang, Yi-Fan Zhu, Ze-Shi Li, Xin-Yi Jiang, Hai-Tao Zhang, He Zhang, Ya-Peng Wang, Wei Chen, Li-Chong Lu, Min Ge, Yong-Qing Cheng, Dong-Jin Wang, Qing Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
sivelestat
cardiopulmonary bypass
acute lung injury
cardiovascular surgery
outcomes
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1082830/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1082830/full

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