New acetylcholinesterase inhibitors isolated from Delphinium uncinatum

New acetylcholinesterase inhibitors isolated from Delphinium uncinatum

The inhibition of acetylcholinesterase (AChE), the key enzyme in the breakdown of acetylcholine, is presently the most common pharmacological approach available for Alzheimer’s disease (AD). Despite research on the molecular bases of AD, potent therapeutic agent against its expansion is still needed...

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Bibliographic Details
Main Authors: Nadia Gul, Shujaat Ahmad, Hanif Ahmad, Abdul Aziz, Mazen Almehmadi, Ahad Amer Alsaiari, Mamdouh Allahyani, Zainab, Syed Adnan Ali Shah, Najeeb Ur Rahman, Manzoor Ahmad
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Arabian Journal of Chemistry
Subjects:
Norditerpenoids
Uncinatine B-D
Alzheimer’s disease (AD)
Acetylcholinesterase inhibitory potential
Molecular docking
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535222007249

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http://www.sciencedirect.com/science/article/pii/S1878535222007249

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