Mesenchymal stem cell therapies for intervertebral disc degeneration: Consideration of the degenerate niche

Abstract We have previously reported a synthetic Laponite crosslinked poly N‐isopropylacrylamide‐co‐N, N′‐dimethylacrylamide (NPgel) hydrogel, which induces nucleus pulposus (NP) cell differentiation of human mesenchymal stem cells (hMSCs) without the need for additional growth factors. Furthermore...

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Bibliographic Details
Main Authors: Louise Vickers, Abbey A. Thorpe, Joseph Snuggs, Christopher Sammon, Christine L. Le Maitre
Format: Article
Language:English
Published: Wiley 2019-06-01
Series:JOR Spine
Subjects:
Online Access:https://doi.org/10.1002/jsp2.1055